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Pathways Recommended:	Vitamin D Related/Nuclear Receptor

Results for "

Vitamin-D receptor (VDR)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	VD/VDR (19) Apoptosis (3) Endogenous Metabolite (2) Isotope-Labeled Compounds (1) RAR/RXR (1) Sodium Channel (1)
By Research Areas:	Cancer (9) Endocrinology (1) Infection (1) Inflammation/Immunology (3) Metabolic Disease (6) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: VD/VDR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147337

MeTC7 1 Publications Verification	VD/VDR	Cancer
MeTC7 is a **Vitamin-D receptor (VDR)** antagonist. MeTC7 has potent VDR inhibition activity with an IC₅₀ value of 2.9 μM. MeTC7 shows good antitumor effects .

HY-76814

Calcitriol-d6	VD/VDR	Metabolic Disease
Calcitriol-d₆ is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR)[1].

HY-10002

Calcitriol Maximum Cited Publications 38 Publications Verification 1,25-DihydroxyVitamin D3	VD/VDR Endogenous Metabolite	Cancer
Calcitriol is the most active metabolite of vitamin D and also a **vitamin D receptor** (VDR) agonist.

HY-75041

Calcitriol Impurities A	VD/VDR	Metabolic Disease
Calcitriol Impurities A is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-77274

Calcitriol Impurities D	VD/VDR	Metabolic Disease
Calcitriol Impurities D is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-10002S

Calcitriol-13C3 1,25-DihydroxyVitamin D3-¹³C₃	Isotope-Labeled Compounds Sodium Channel	Neurological Disease
Calcitriol- ¹³C₃ is the ¹³C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

HY-13293

Impurity C of Calcitriol	VD/VDR	Cancer
Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-13292

Impurity B of Calcitriol 1β,25-DihydroxyVitamin-D3; 1-Epicalcitriol	VD/VDR	Cancer
Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-15329

Maxacalcitol-d6	VD/VDR	Metabolic Disease
Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.

HY-107218

11-Hydroxysugiol

RAR/RXR VD/VDR Infection

11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D₃ receptor (VDR) .

11-Hydroxysugiol	RAR/RXR VD/VDR	Infection
11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D₃ receptor (VDR) .

HY-10002S1

Calcitriol-d3 1,25-DihydroxyVitamin D3-d₃	VD/VDR Endogenous Metabolite	Cancer
Calcitriol-d₃ is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist[2][3][4][5].

HY-149899

VDR agonist 2	VD/VDR	Others
VDR agonist 2 (compound 16i) is a *VDR* (vitamin D *receptor) agonist that can effectively inhibit TGF-β1-induced activation of hepatic stellate cells (HSC). VDR* agonist 2 has significant anti-hepatic fibrosis effects both in vitro and in vivo .

HY-114310

VDR agonist 1	VD/VDR Apoptosis	Cancer
VDR agonist 1 (compound 28) is a nonsteroidal **Vitamin D receptor (VDR) agonist, with an IC₅₀** of 690 nM in MCF-7 cells. VDR agonist 1 arrests the cell cycle through the up-regulation of p21 and p27, promotes apoptosis by increasing the expression of BAX and decrease the expression of Bcl-2 .

HY-103053

PS121912	VD/VDR Apoptosis	Cancer
PS121912 is a selective **vitamin D receptor (VDR)-coregulator** inhibitor. PS121912 has acceptable metabolic stability in vivo. PS121912 can be used for the research of cancer .

HY-32345

Elocalcitol BXL-628; Ro-26-9228	VD/VDR	Inflammation/Immunology Cancer
Elocalcitol (BXL-628) is a selective, orally active **vitamin D receptor (VDR)** agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells .

HY-12398A

TEI-9648	VD/VDR	Metabolic Disease Inflammation/Immunology
TEI-9648, a Vitamin D₃ Lactone analogue, is a potent and specific **vitamin D receptor (VDR)** antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)₂D₃. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)₂D₃. TEI-9648 has the potential for bone metabolism research .

HY-32344

Inecalcitol TX 522	VD/VDR Apoptosis	Cancer
Inecalcitol (TX 522), a unique vitamin D3 analog, is an orally active **vitamin D receptor (VDR) agonist with a K_d of 0.53 nM. Inecalcitol can induce cell apoptosis** and has potent anticancer activities . Inecalcitol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-12398

TEI-9647	VD/VDR	Metabolic Disease Inflammation/Immunology
TEI-9647, a Vitamin D₃ Lactone analogue, is a potent and specific **vitamin D receptor (VDR)** antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)₂D₃. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH)₂D₃. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease .

HY-10002A

(1S)-Calcitriol 1α,25-Dihydroxy-3-epi-Vitamin-D3	VD/VDR	Others
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D₃ (1α,25(OH)₂D₃). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-12397

ZK159222 1 Publications Verification	VD/VDR	Endocrinology
ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-10002

Calcitriol 35+ Cited Publications 1,25-DihydroxyVitamin D3	Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	VD/VDR Endogenous Metabolite
Calcitriol is the most active metabolite of vitamin D and also a **vitamin D receptor** (VDR) agonist.

Species:	Human (1) Mouse (1)
Tag:	His (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P73542

	Vitamin D Receptor/VDR Protein, Mouse (sf9, His) Vitamin D3 receptor; VDR; NR1I1	Mouse	Sf9 insect cells
	Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol, which translocates to the nucleus after binding vitamin D3, thereby coordinating cellular activities. VDR forms a heterodimer with RXR, binds to DNA response elements, and initiates the transcription of vitamin D3-responsive genes. Vitamin D Receptor/VDR Protein, Mouse (sf9, His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Vitamin D Receptor/VDR Protein, Mouse (sf9, His) is 422 a.a., with molecular weight of ~55 kDa.

HY-P73543

	Vitamin D Receptor/VDR Protein, Human (sf9, His) Vitamin D3 receptor; VDR; NR1I1	Human	Sf9 insect cells
	Vitamin D receptor (VDR) acts as a nuclear receptor for calcitriol, the active form of vitamin D3, triggering cellular effects. After vitamin D3 binding, VDR translocates to the nucleus and forms a heterodimer with the retinoid X receptor (RXR). Vitamin D Receptor/VDR Protein, Human (sf9, His) is the recombinant human-derived Vitamin D Receptor/VDR protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Vitamin D Receptor/VDR Protein, Human (sf9, His) is 427 a.a., with molecular weight of ~50 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-76814

Calcitriol-d6

Calcitriol-d₆ is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR)[1].
HY-10002S

Calcitriol-13C3

Calcitriol- ¹³C₃ is the ¹³C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
HY-15329

Maxacalcitol-d6

Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.
HY-10002S1

Calcitriol-d3

Calcitriol-d₃ is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist[2][3][4][5].

Calcitriol-d6
Calcitriol-d₆ is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR)[1].

Calcitriol-13C3
Calcitriol- ¹³C₃ is the ¹³C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

Maxacalcitol-d6
Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.

Calcitriol-d3
Calcitriol-d₃ is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist[2][3][4][5].

Vitamin D Receptor Antibody Vitamin D3 receptor; 125 dihydroxyVitamin D3 receptor; 1 antibody 1,25-@dihydroxyVitamin D3 receptor; 125 dihydroxyVitamin D3 receptor; 25-dihydroxyVitamin D3 receptor; NR1I1; Nuclear receptor subfamily 1 group I member 1; VDR; VDR_HUMAN; Vitamin D (1,25- dihydroxyVitamin D3) receptor; Vitamin D hormone receptor; Vitamin D receptor; Vitamin D3 receptor,	IHC-P; IHC-F; ICC; IF	Human, Rat(predicted: Mouse, Chicken, Pig, Cow, Horse, Rabbit)
Vitamin D Receptor Antibody is an unconjugated, approximately 47 kDa, rabbit-derived, anti-Vitamin D Receptor polyclonal antibody. Vitamin D Receptor Antibody can be used for: IHC-P, IHC-F, ICC, IF expriments in human, rat, and predicted: mouse, chicken, pig, cow, horse, rabbit background without labeling.

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Vitamin-D receptor (VDR)

Inhibitors & Agonists

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
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